The protooncogene c‐myc encodes a protein that is a central regulator of cell growth, differentiation, proliferation and apoptosis.7 Overexpression of c‐myc is associated with various cancers like colon, breast, cervix and small cell lung carcinomas.8 Expression of c‐myc is mainly controlled by the nuclear hypersensitivity element III1 (NHE III1), that is located −142 to −115 base pairs upstream the P1 promoter.9 The template strand of NHE III1 contains the G‐rich sequence Pu27 that is able to form a G4. Here, MYC is linked to cancer.