Eya1-Six1-Dach and Eya1-Hox11-Pax2 complexes during the early stages of MM activate expressions of SIX2 and GDNF in the mesenchymal progenitors (Li et al., 2003; Gong et al., 2007; Xu et al., 2015). The gene discussed is EYA1; the disease is Miyoshi myopathy.