TGFB1 and myocardial infarction: Furthermore, as previously mentioned, after MI, upregulated miR-29a and miR-101a restrained the TGFβ-1/Smad2/3 and fos/TGFβ-1 pathways via aerobic exercise, eventually inhibiting myocardial interstitial fibrosis (Xiao et al., 2017).