Therefore, A group of associated atherosclerosis genes was regulated, endothelin 1 (EDN1), angiotensin II (ANGII), as well as thromboxane A2 (TxA2) downregulated and endothelial nitric oxide synthase (eNOS), prostacyclin (PGI2), and VEGF upregulated (Wang et al., 2017). The gene discussed is AGT; the disease is atherosclerosis.