MYC and Burkitt lymphoma: Phosphorylation of Thr58 of c-Myc is critical for its oncogenic potential, since a mutation at Thr58 is often identified in the amplified c-myc genes in Burkitt’s lymphoma and Thr58 mutant of c-Myc demonstrates enhanced oncogenic potential with increased protein stability (Farrell and Sears, 2014).