FN1 and myocardial infarction: Although fibronectin decreases with developmental age, it is still required in the adult heart for providing structural support by linking the cardiac interstitium with the basement membranes of endothelial and muscle cells and for the reparative response following a myocardial infarction (Borg et al., 1984; Kim et al., 1999; Konstandin et al., 2013).