Downregulation of both NKp30 and NKp46 has been described in HCMV infection (Guma et al., 2004), yet here, among our HCMV+ participant groups, we observed progressive downregulation of NKp46 from the highest expression levels in Mtb-naïve U.S. adults, to intermediate levels in QFT− Kenyan adults and finally the lowest NKp46 expression in QFT+ Kenyan adults. The gene discussed is NCR1; the disease is cytomegalovirus infection.