LDHA and pancreatic intraductal papillary-mucinous neoplasm: Upon Akti treatment, alteration in stem cell contents occurred as well: as can be seen in Figure S7, when cell density reached 106 cells/ml under 45 min of incubation time, a greater drop of Aldh+ cells in Akti-treated IPMN than in PanIN can be observed (Figure S7A; P < 0.05).