Moreover, critical reviews regarding the potential candidates highlighted so far, have reduced the list of best candidates to a few molecules that have already a known link to the PD pathogenesis and other neurodegenerative diseases, such as the protein DJ-1, oligomerized α-synuclein, tau, phospho-tau, amyloid β1–42 [for concise reviews on this topic consult [5, 6, 51]]. Here, MAPT is linked to Parkinson disease.