Growth hormone administration seemed to have worsened the lymphoproliferation.<h4>Conclusions</h4>Patients with suspected common variable immunodeficiency (CVID) and additional symptoms, such as allergy, facial dysmorphia, short stature, enhanced lymphoproliferation and lack of adequate response to human immunoglobulin replacement therapy, should be considered for NGS-based genetic testing. Here, GH1 is linked to common variable immunodeficiency.