Interestingly, although no significant correlation was shown between PXMP4 expression and Topotecan IC50 values, there was a significant lower expression of PXMP4 in the Topotecan-sensitive NSCLC cell lines than the resistant ones (Figure 10C), indicating that the expressional difference of PXMP4 might be due to the differences between the two groups but not due to the drug itself. Here, PXMP4 is linked to non-small cell lung carcinoma.