CCNB2 and hepatocellular carcinoma: Furthermore, CCNB2, MAD2L1, BUB1, and NCAPG are significantly upregulated in hepatocellular carcinoma (HCC) tissues and are implicated in the growth and metastasis of HCC cells (Li et al., 2017, 2019; Xu et al., 2017; Liu K. et al., 2018).