TNF and sporotrichosis: Patients with sporotrichosis showed markedly higher serum levels of TNF and IL-6 than healthy controls (HC; Figure 7; TNF-α: 53 ± 24 vs. 6 ± 10 pg/ml, P < 0.001; IL-6: 80 ± 42 vs. 25 ± 10 pg/ml, P < 0.001).