At the same time, aerobic exercise and DNase administration reduced BALF levels of inflammatory cytokines including interleukin (IL) IL-1β, IL-6, and tumor necrosis factor alpha (TNF-α) in LPS-induced ALI compared to LPS alone mice (p < 0.05 and p < 0.01), with an increase in the anti-inflammatory cytokine IL-10 (p < 0.001 and p < 0.01) (Figure 3D). This evidence concerns the gene TNF and acute respiratory distress syndrome.