Further characterization revealed stronger immunofluorescent staining for activated NF-κB, chemokines (e.g., CXCL10 and CCL5), and C3d located within the hypertrophic astrocytes and greater perivascular T lymphocyte infiltration in MS lesions with the rs7665090 risk than those with a protective genotype (30). The gene discussed is NFKB1; the disease is myeloid sarcoma.