GAL has also been detected in a variety of non-neuroendocrine human tumors of different origin, including glioblastoma and other brain tumors (21), melanoma (22), head and neck squamous cell carcinoma (HNSCC) (23), basal cell carcinoma (24), colon cancer (25–27) and embryonic carcinoma (28). Here, GAL is linked to head and neck squamous cell carcinoma.