In addition, a number of studies have demonstrated the significant beneficial effects of EPO in various experimental models of ALI/ARDS, including experimental ALI/ARDS caused by acute necrotizing pancreatitis (Tascilar et al., 2007), ischemia-reperfusion (Wu et al., 2006, 2009), experimental sepsis induced by cecal ligation and puncture (Heitrich et al., 2016), LPS (Shang et al., 2009), and zymosan-induced non-septic shock (Cuzzocrea et al., 2006). Here, EPO is linked to acute respiratory distress syndrome.