PDGFRB and Alzheimer disease: On the other hand, pericyte coverage showed a significant reduction of PDGFR-β immunoreactivity in AD patients compared to controls both in the GM: −63% (Ctrl: 0.408 ± 0.110, AD: 0.149 ± 0.097, p = 0.004) and in the white matter −64% (Ctrl: 0.721 ± 0.231, AD: 0.256 ± 0.137, p = 0.004).