CLEC3B and large cell carcinoma: The results showed a significant downregulation of CLEC3B in several histological subtypes (p < 0.001), including ADC, SCC, large-cell carcinoma (LCC), large-cell neuroendocrine tumor (LCNE) and small-cell lung cancer (SCLC) compared with noncancerous lung tissues in GSE30219 (Fig. 1a).