To clarify the functional significance of TARC in IgG4-RD, we further examined the correlation between the serum concentration of TARC and clinical parameters in the patients with IgG4-RD including the serum IgG4, IgG, and IgE concentrations, the eosinophil count, the IgG4-RD RI score, the number of organs involved, and allergic history. Here, IGHE is linked to immunoglobulin G4-related sclerosing disease.