As shown in Table 5, these subjects exhibited no germline variants or mutations in exon 9 or exon 15 of PLCD1. Interestingly, only half of these cysts showed the p.S745L somatic mutation in exon 15 of PLCD1 as compared to 100% of the familial trichilemmal cysts. Here, PLCD1 is linked to Follicular Cyst.