ESS2 and Down syndrome: NGM analysis of two mutants placed in the hfg7 group revealed mutations in the gene encoding DGCR14-like [DiGeorge Syndrome Critical Region, also termed ESS2 (Expression Studies2) in humans (Lindsay et al., 1996) and EsS-2 (ES2-Similar) in Caenorhabditis elegans (Noma et al., 2014)].