ANPEP and neoplasm: In contrast, MI130110 did not induce any effect on the cell cycle of the CD13-negative non-tumor endothelial EA.hy926 cells as the percentage of cells in G2 did not change with time (24 or 48 h) in the presence or in the absence of the ADC concentrations under study (1 μg/mL and 10 μg/mL), remaining at basal levels (Fig. 3b, right hand panels).