In the present study, a total of 22 ARGs were significantly associated with DFS of PCa in multivariate Cox regression analysis, including ULK2, NLRC4, MAPK1, ATG4D, MAPK3, ATG2A, ATG9B, FOXO1, PTEN, HDAC6, PRKN, HSPB8, P4HB, MAP2K7, MTOR, RHEB, TSC1, BIRC5, RGS19, RAB24, PTK6, and NRG2. Here, HDAC6 is linked to posterior cortical atrophy.