Interestingly, there was a statistically significant decrease in all CAMs (E-selectin, ICAM-1, and VCAM-1) measured in the peripheral blood in patients who improved clinically on the 4th day compared with the levels on admission, but patients who did not improve had more severe cerebral infarcts, a higher NIHSS score on admission, and no change was observed in levels of CAMs during the short follow-up period [28], suggesting the reduction in CAMs within the first few days of hospitalization may predict a favorable outcome in patients with acute cerebral events. The gene discussed is VCAM1; the disease is brain infarction.