Remarkably, the loss of DLG1 expression at cell to cell contact (normal localization), together with an increase in DLG1 levels and unusual cytoplasmic distribution [15, 16], were also detected in biopsies derived from other tumours, like colon adenocarcinoma [16, 36] and breast cancer [37, 38]. The gene discussed is DLG1; the disease is breast carcinoma.