As observed with Tfh cells, DENV-specific IgM antibody titres did not correlate with the frequency of plasmablasts in patients with DF (Spearman r = 0.27, p = 0.26) or in DHF (Spearman r = 0.21, p = 0.34) (Fig. 5c). This evidence concerns the gene CD40LG and dengue disease.