We also evaluated functionality of the tumor vasculature in our model with a passive permeability marker 14C-aminoisobutyric acid (14C-AIB, MW = 103.12) and a P-glycoprotein (P-gp) substrate Oregon Green (OG, MW = 509.38), as well as albumin-bound vascularity marker indocyanine green (IR-820, ICG). The gene discussed is PGP; the disease is neoplasm.