In order to figure out characteristics of host's immune response to the virus, immunological status of 11 SARS-CoV-2 infected patients with ARDS were analyzed by Wang et al. (14) and found that, while CD4 and CD8 T lymphocytes were significantly decreased, IL-6 was significantly increased in critically ill patients, and IL-6 should be an early predictor of severe disease. Here, IL6 is linked to acute respiratory distress syndrome.