PPARG and hydrops fetalis: However, HF feeding significantly upregulated the gene expression of peroxisome proliferator-activated receptor gamma (PPARγ), a transcription factor for adipogenesis, compared to the LF group (LF vs. HF, p < 0.05); this was significantly decreased by 10% 2′-FL supplementation (HF_10% 2′-FL vs. HF, p < 0.01; Figure 6D).