However, our findings might be useful for clinical practice in distinguishing cachectic patients with CHF (by measuring Cm by BIA and laboratory parameters- irisin, albumin, CRP) in order to monitor these patients more accurately, as the diagnostic accuracy is very high (sensitivity of 93.3% and specificity of 85.3%; AUC = 0.929). This evidence concerns the gene FNDC5 and congestive heart failure.