Inhibition of ILK/AKT decreases miR-21 in vestibular schwannoma and meningioma cells [42], and targeting miR-21 with antisense oligonucleotides (ASOs) inhibits growth and metastasis via upregulation of DUSP8 in colorectal carcinoma [43]. This evidence concerns the gene AKT1 and Vestibular schwannoma.