THPO and Thrombocytopenia: Although we could not demonstrate the causality between the presence of the anti-THPO antibody and decreased platelet count in this study, a previous report indicated the direct effect of the anti-THPO antibody on thrombocytopenia [14]; in that study, the anti-THPO antibodies might have blocked the normal function of thrombopoietin and resulted in decreased platelet production.