Increased action of GnT-V was also observed with a more aggressive NB phenotype, since increased levels of β1,6-branched N-glycans, along with a decline in hybrid-type N-glycans, were found in cells derived from high-risk neuroblastoma (NLF) compared to cells derived from low-risk neuroblastoma (SY5Y) [12]. This evidence concerns the gene MGAT5 and neuroblastoma.