MYC and lung cancer: Importantly, 3 days of treatment with 2.37 mg/kg Omomyc reduced proliferation of tumor cells (detected by Ki67 positivity), caused a shutdown of several gene sets related to Myc activation and poor lung cancer prognosis, among others, and induced changes in chemokine and cytokine profiles, consistent with Myc’s role in modulating the tumor microenvironment.