Importantly, although the protein expression profile did not explain the differences in migration of colon cancer HT-29 and LS-180 cells (Figure 7), the immunofluorescent staining revealed nuclear translocation of N-cadherin in HT-29 cells exposed to 8-hydroxyquinaldic acid for 48 h (Figure 8). This evidence concerns the gene CDH2 and colonic neoplasm.