The interplay between bacterial and fungal virulence factors in a mixed biofilm formed at the infection foci, including the joint action of P. gingivalis enzymes―gingipains and PPAD―in the process of citrullination of human proteins―HPG and HK―that adhere to C. albicans cell surface, may be an important element of the pathogenesis mechanisms of these microbes. Here, KNG1 is linked to infection.