Bibliographic research about the role of miR-92a-3p and miR-181a-5p in BC and particularly in TNBC demonstrated that whereas miR-92a-3p has not been studied yet, in breast cancer it regulates ERβ expression, as a significant negative correlation between its expression and both ERβ mRNA and protein expression levels was demonstrated on a cohort of primary breast tumors [70]. The gene discussed is ESR2; the disease is breast cancer.