VDR and Hypercalciuria: The present study does not address the time of appearance of the increased bone resorption in the GHS rats; however, the hypercalciuria is present as early as 6 weeks of life upon completion of weaning, and the hyper‐response of bone resorption to 1,25(OH)2D3 and the high bone cell VDR content are present in calvariae of 2‐day‐old pups from GHS mothers.26 Thus, the functional changes in GHS bone cells may be lifelong.