A small molecule inhibitor of SND1, 3’, 5’-deoxythymidine bisphosphate (pdTp), significantly inhibited growth of orthotopic xenografts of human HCC cells in nude mice accompanied by decrease in markers of TIC and inflammation, thereby confirming SND1 as a potential therapeutic target for HCC and utility of pdTp as a therapeutic agent[43]. Here, SND1 is linked to hepatocellular carcinoma.