Chung et al. have identified an upregulation of proinflammatory cytokines such as IL-6, IL-β, and TNF-α and have documented a potential underlying molecular mechanism, namely, the NF-κB-dependent network which is associated with numerous age-related diseases including dementia, cardiovascular disease, and osteoporosis [36]. The gene discussed is NFKB1; the disease is cardiovascular disorder.