Our results revealed that 4 novel loci of GBE1/LINC02027 (rs117503120), TIMP3/SYN3 (rs5998634), TENM4 (rs4483616), and RBM45/OSBPL6 (rs16866133) were strongly associated with ITP from CHP. The gene discussed is SYN3; the disease is autoimmune thrombocytopenic purpura.