TENM4 and autoimmune thrombocytopenic purpura: According to the Bonferroni correction for multiple tests, the top four loci (rs117503120, rs4483616, rs5998634, and rs16866133) located within or near GBE1/LINC02027, TENM4, SYN3/TIMP3, and RBM45/OSBPL6 genes reached a statistical significance in association with ITP in the genome-wide scale (P < 1.0 × 10−7, Figure 1, Table 2).