Furthermore, mutations in Strumpellin and SWIP have been linked with multiple neurological disorders, including intellectual disability, hereditary spastic paraplegia, and Ritscher-Schinzel/3C syndrome (Valdmanis et al., 2007; Ropers et al., 2011; Vardarajan et al., 2012; de Bot et al., 2013; Elliott et al., 2013). This evidence concerns the gene WASHC5 and hereditary spastic paraplegia.