TP53 and liver cancer: For example, SNHG1 was found to promote liver cancer development through inhibiting p53 expression via binding to DNMT1 (44); Lan et al. (45) demonstrated that SNHG12 facilitated tumorigenesis and metastasis by targeting miR-199a/b-5p in hepatocellular carcinoma (45); LINC00511 contributed to cell proliferation and metastasis by modulating miR-424 in hepatocellular carcinoma (46); SNHG16 was also reported to enhance proliferation, migration and invasion of hepatocellular carcinoma (47–49).