Similarly in the another dataset CGGA mRNAseq_325, univariate analysis revealed that a total of 9 factors were associated with OS of gliomas, including TNFRSF1A expression, age, WHO grade, PRS_type, histology, Radio_status, Chemo_status, IDH_mutation_status and 1p19q_codeletion_status (Table 2). Here, IDH1 is linked to central nervous system cancer.