CRP and Insulin resistance: Recent research has focused on a phenotype of obese individuals, termed the MHO, referring to obese subjects with less than 2 risk parameters of the metabolic syndrome (except accounting for waist circumference) and elevated homeostatic model for assessing insulin resistance (HOMA-IR) and elevated c-reactive protein (CRP) levels, which is now being widely used (Stefan, Schick & Haring, 2017).