PD-associated loci, scavenger receptor class B member 2 (SCARB2) rs6812193 and microtubule associated protein tau (MAPT) rs12185268 are also associated with RBD, while homozygous carriers of the ubiquitin specific peptidase 25 (USP25) rs2823357 single-nucleotide polymorphism (SNP) show a more rapid progression to synucleinopathy [40]. The gene discussed is USP25; the disease is Parkinson disease.