Furthermore, we established a HepG2 tumor-bearing xenograft mouse model to examine the antitumor effect of atorvastatin in vivo and observed that atorvastatin suppressed tumor growth and that the expression patterns of IL-6, STAT3, TERT, and β-gal, along with β-gal activity, were similar to those observed in in vitro studies. The gene discussed is STAT3; the disease is neoplasm.