Univariate and multivariate analyses revealed that, along with γ-glutamyl transferase test results, tumor size, tumor number, and microvascular invasion, the MACROD2 expression level was an independent prognostic factor for both overall survival (OS) [P < 0.001, hazard ratio (HR) = 0.502] and time to recurrence (TTR) (P < 0.001, HR = 0.567; Table 2). The gene discussed is MACROD2; the disease is neoplasm.