H2AX and breast carcinoma: This in-depth review on the study of different epigenetic modifiers in the context of breast cancer metastasis led to the formulation of a panel of epigenetic factors namely APLF, HJURP, MacroH2A.1, ɣH2AX and H2Bub1, that could be exploited to detect the potential of breast cancer to become metastatic in nature.