Underlying lung disease, plasma albumin, serum creatinine level, number of organs with failure, and IMV duration fit into the regression equation, indicating that the five parameters were independent factors influencing the weaning success rate for MODSE patients receiving IMV, with odds ratios (ORs) of 1.447, 0.820, 1.603, 2.374, and 3.105, respectively (Table 4). This evidence concerns the gene ALB and lung disorder.